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Preclinically, nsPEF-mediated local ablation in murine melanoma models restores (though does not enhance) dormant antitumor immunity in tumor-bearing hosts (65), while nsPEF treatment induces non-cytotoxic membrane permeabilization and morphological changes characterized by vesicle externalization, cell contraction, and lipid migration

PMF and JBH were supported by NIH grant DP2 GM123641, and PMF is a Chan Zuckerberg Biohub Investigator

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